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C.R.I. of Paris

Life Sciences Bachelor (2018-2021)

In this formation, I have the opportunity to learn about general science but more particularly life sciences by studying in a  world of research and understand the place of science in society. The program is based on a common core of mathematics, physics, chemistry, computer science and biology in order to approach life sciences in all their facets.
Here is my presentation of the FdV Bachelor (in french): https://www.youtube.com/watch?v=ePJez0bbS28

 

Projects & internships as part of C.R.I.

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edX - HarvardX

This MOOC was an introduction to the study of bioethics and the application of legal and ethical reasoning. It was given by I. Glenn Cohen from Harvard Law School. During this course, I learned about bioethics which provides an overview of the legal, medical, and ethical questions around reproduction and human genetics and especially, how to apply legal reasoning to these questions.

This law course included interviews with individuals who have used surrogacy and sperm donation, with medical professionals who are experts in current reproductive technologies like In Vitro Fertilization and Preimplantation Genetic Diagnosis, and bioethicists and journalists who study the ownership and use of genetic information within human tissue. Finally, Harvard teachers shared their thoughts on topics such as disability law as it relates to reproductive technology.

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Laboratory projects and courses

Chemistry, Physic & Biology

In the C.R.I. Laboratory, I had the opportunity to discover all the equipment and techniques. I get familiarized with PCR, electrophoresis, DNA extraction, cellular culture, ELISA test, dissection, ...

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Internship in Virology & Immunology Laboratory

Saint-Antoine Hospital, Paris

During this internships, I discovered the job of laboratory technician but also biologist. I sorted and centrifuged the patients blood tubes when they were delivered then putted them into automates. These automates were checking the presence of sexually transmitted diseases such as: HIV, Hepatitis A, B, C, E, syphilis, etc. When the results were positive, a second analyze was made by hand, I helped for hepatitis E & syphilis. Finally, I reported the results to the biologist which was giving his/her final conclusion to the doctor of the patient concerned. My internships presentation can be found right there.

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Work on preimplantation diagnosis

During this project, I had to make research on the researches made on the preimplantation diagnosis and the ethics side. To do so, I read a lot of scientific articles in French, English & Spanish and I wrote a paper entitled 'Le diagnostic préimplantatoire (DPI), à l'ère de la médecine prédictive' available right here.

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IFREMER - AQUATHON, Brest

In the context of the Aquathon - Brest 2019, I developed with classmates a citizen science project in order to collect, observe and identify plankton in the "Rade de Brest". We made a microscope and a plankton net with materials that we can find easily. All is centralized in that report. We also developed a website and a game with the aim of list all the plankton observations on a France map.

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Self-tracking experiment

Team of Bastian Greshake Tzovaras - Fellow at C.R.I.

Have you ever wondered why you are in such a terrible mood? This is what I tried to figure out during the past semester with a classmate and a researcher by analyzing our personal daily data. We created a google form composed of different sections (such as sleep, food, social interactions etc.) which could impact our mood without being aware. After having collected our daily data for 3 months, we plotted several graphics thanks to RStudio. We observed that the sport, the social interactions and our sleep quality actually impacted our mood at specific scales. Our work can be found here.

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Nanopore Sequencing

Research work and presentation of this NGS

Work on the nanopore sequencing which is a NGS (Next-Generation Sequencing). I studied with classmates the properties, the technologies and the application of using a nanopore in order to sequence a mammalian-size genome. The final presentation is available here.

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Caenorhabditis elegans

Poster realization

I had the opportunity to work on C. elegans as a model in order to understand research applications. I tackled many aspects such as its physiology, its phylogeny, advantages / disadvantages and example of application. The final poster can be found here.

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Antoine Taly, CNRS researcher

During this project, the goal was to produce our own biology course. I choose with other classmates to work on the Immune System. We made several researches & drawings in order to have the more information and in a logical way to be learned by our classroom. All was published on a website[under maintenance].

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COVID-19 case

Due to the Coronavirus pandemic, our biology exam became a homework which aims at follow up our own biology course. I tackled a therapeutic approach by interferon-mediated immune response in order to fight SARS-CoV-2 available on the same website[under maintenance]. My work is downloadable here.

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Reproducibility of a scientific experiment

Alessandro Donada (PhD, Institut Curie)

Atelier des jours à venir

In team of 5, the goal was to reanalyze the datasets that Alessandro Donada used to answer is research problematic which is 'How much time does a hematopoietic cell take to make a cellular cycle?'.
We then make him a feedback on how much his experiment was reliable, reproducible and robust.

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Team of Bastian Greshake Tzovaras

Open Humans Foundation

This project aims at collect symptoms data in order to know if whether the flu or common cold, can wearables warn us when we're getting sick? To do so, I coded on Rstudio in order to implement  data by representing visualizations. As part of the Open Humans Foundation, I had the opportunity to exchange with researchers. The final presentation and the daily diary are available.

Here is  the Open Humans Foundation where, with a classmate, we presented our work: https://www.youtube.com/watch?v=Yvm2kQgDsS0

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SDG project

C.R.I. MakerLab

During this project, I tackled with teammates how to improve a particular aspect post COVID-19 lock down. We thought about add airtight tarpaulins zippable in the ambulance cabin. Our presentation can be found right here.

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Internship in a Clinical Research Center (CRC)

Intercommunal Hospital Center of the city of Créteil (CHIC), Ile-de-France

I did an internship at the CRC and had the opportunity to interact with the Respirology department. Indeed, I was in charge of the follow-up of clinical trials on bronchial cancer (KBP-2020-CPHG and AMG510).

I also helped in the creation of protocols and information notes to be delivered to patients. I was immersed in the radiotherapy and pharmacy department which allows me to see several facets of the organization of clinical trials. Finally, I have been able to observe interventions in pneumology and participate in protocol launches and multidisciplinary consultation meetings.

All my internship project is available here.

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I did this MOOC focusing on Ethic in Public Health, questioning the place of ethic in all the health practices, from vaccine cases to drugs addictions, from tabagism to blood shortage. It also approaches disparities, health on a global scale and ecological health. I obtained the certification on 01/29/2021.

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Internship at the Biomedicine Agency

Research Department - supervised by Mr Samuel Arrabal

I worked on CRISPR technic by taking into considerations all the ethical and technical issues. The goal is to establish recommandations and obtain an overview of policies on a global scale. This work could contribute to the Bioethics French Law. Here is the link where my project is described: https://projects.cri-paris.net/projects/hIubFPl6/summary

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MOOC "Foundations of Public Health Practice: The Public Health Approach"

Imperial College London - Coursera

The Public Health Approach course is the first instalment of the wider Foundations of Public Health Practice specialisation from Imperial College London's Global Master of Public Health (MPH). Through short video lectures, practitioner interviews and a wide range of interactive activities, I was immersed in the world of public health practice. The 'Public Health Approach' is a phrase that is used widely to describe an up-stream, preventive, values-driven and evidence-based approach to improving population health.